Biosimilar switching

Every minute of friction slows the switch.

A payer contract prompts patients to move from the brand to a biosimilar, but each switch has to clear provider intake and patient enrollment. Friction is the minutes each task takes; stalled switches default back to the brand.

Switch completion, program

62%

baseline 38%

Months to half the gap

3.2

baseline 4.9 · none 1.9

Extra switches by M12

+85

program vs baseline

Lost per provider minute

1.5

switches by M12, baseline

01

Friction, minutes per task

Minutes to complete each task today (Baseline) and with a streamlined hub (Program).

Provider intake

Office and hub work before the biosimilar Rx can be filled.

Task (minutes)BaselineProgram
Write the biosimilar Rx
Prior authorization
Benefits verification
Counsel patient on the switch
Specialty pharmacy referral
Total minutes7033
Completes58%78%
Half of intakes stall atM½90 min

Patient enrollment

Patient work before the first biosimilar dose.

Task (minutes)BaselineProgram
Support program enrollment
Copay assistance sign-up
Consent and HIPAA forms
Injection device training
Pharmacy onboarding call
Total minutes7540
Completes65%79%
Half of patients stall atM½120 min
02

Switch variables & impact

How friction changes who switches, how fast, and who is lost.

Patients on the biosimilar over 12 months

No frictionBaseline frictionProgram friction
Inertia, payer drives the switchλ′0.70
Unlocked shareS*50%
Starting biosimilar shareS₀0%
Lost from therapy when a switch stallsd10%

Each month the payer contract prompts (1 − λ′) of the remaining gap to switch. λ′, S* and S₀ are shared with Share velocity on the Velocity page.

Friction-adjusted switching

cp = 0.5Mp/M½p   ce = 0.5Me/M½e

vt = (1 − λ′) × cpce × remaining gap

lostt = (1 − λ′) × (1 − cpce) × d × remaining gap

M is total minutes across the tasks and M½ the minutes at which half of switches stall. Stalled switches default back to the brand, except the share d lost from therapy.

Impact by month 12No frictionBaselineProgram
Provider intake minutes07033
Patient enrollment minutes07540
Provider completes intake100.0%58.3%77.6%
Patient completes enrollment100.0%64.8%79.4%
Switch completes100.0%37.8%61.6%
Months to close half the gap1.94.93.2
Switched by month 12493351436
Lost from therapy by month 1205827
Biosimilar patient-months, year 14,8492,8473,860
Switches lost per extra provider minute0.61.51.2
Switches lost per extra patient minute0.51.10.9